Small Ruminant Dewormer Drug Classes
Amy Barkley, Livestock Specialist
Southwest New York Dairy, Livestock and Field Crops Program

Dewormer Classes for Small Ruminants
By Amy Barkley, Livestock Specialist, SWNYDLFC
Information from the American Consortium for Small Ruminant Parasite Control
Resistance to dewormer classes is a real challenge for many sheep and goat producers. Even when performing bi-monthly FAMACHA and 5-Point Checks and using dewormers properly and judiciously, you may still encounter resistance issues. If it's been determined that your herd or flock is resistant to one class of dewormers, it's a good idea to switch dewormer classes and continue using that single class going forward until you develop resistance to it too. It's important to make proper deworming protocols a focus of your operation because there are only three classes of anthelmintics on the market, and there aren't likely to be any additional classes developed any time soon. Once resistance is developed to one class, it's unlikely that you'll lose resistance, so the goal is to gain resistance to the other two classes in as long a time as possible.
What can be confusing about these drugs is that under each active drug class, there are many drug names. To help limit the confusion and to ensure correct identification of drug classes, here are the lists of drug names within each of the three drug classes.
Benzimidazoles: Chemical name ends in a "…dazole".
- Fenbendazole
- Safeguard, Panacur
- Albendazole
- Valbazen
- Oxybendazole
- Synantic
Notes: These are broad spectrum with a wide margin of safety. They are effective against tapeworms. Valbazen is effective against adult liver flukes and should not be administered to pregnant animals.
Nicotinics:
- Levamisole (clear drench)
- Tramisol, Levasole, Prohibit
- Morantel
- Rumatel, Positive Goat Pellet
- Pyrantel
- Strongid
Notes: Rumatel and Pyrantal are only effective against adult worms, while Levamisole is broader spectrum but has a narrower margin of safety.
Macrolides:
- Avermectins
- Ivermectin
- Ivomec, Zimecterin, Eprinex, and Promectin
- Doramectin
- Dectomax
- Ivermectin
- Moxidectin
- Cydectin, Quest
Notes: This class is a broad spectrum dewormer with a wide margin of safety. In addition to use for internal parasites, it's also effective against sucking external parasites. Moxidectin is the newest addition to this class and has persistent activity.
Like with any drug, the label is the law! Review the label for dosing, withdrawals, and animal classes. Some of these may be used extra label with approval from your veterinarian. This is most commonly needed for use in goats.
Upcoming Events
Chainsaw Safety & Forestry BMP's
June 13, 2025
Belmont, NY
Perfect for beginners or experienced users needing a refresher. We'll cover safety features and basic maintenance of the modern saw and learn kickback prevention techniques. Participants will be able to try on various PPE and learn ergonomic practices. Interested participants will learn to safely start up, throttle up, and turn off a saw. You may bring our own saw if you choose, there will be no cutting in this class.
FAMACHA Workshop at Alfred State College
June 14, 2025 : FAMACHA Workshop at Alfred State College
Alfred, NY
Join Cornell Cooperative Extension for a morning of classroom learning, hands-on FAMACHA and 5 Point Check practice, and a pasture walk at Alfred State College's teaching farm to learn about putting IPM to work on pasture using evasive grazing techniques. An exam will be provided, and students passing the exam will receive program certification, including a FAMACHA Card.
Fecal Egg Count Mobile Workshop at Alfred State College
June 17, 2025 : Fecal Egg Count Mobile Workshop at Alfred State College
Alfred, NY
This mobile workshop will teach you what you need to know to perform fecal egg counts and understand the results of fecal egg count reduction tests at home. While focused on testing sheep and goats, this event is applicable to all ruminants and camelids.
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